South Carolina Medicaid Office

Below is the contact information for the Medicaid office in South Carolina. They can assist you with questions or concerns about the South Carolina Medicaid program, including the eligibility requirements and Medicaid enrollment in South Carolina. You can view their site online at To find out if you are eligible for this program, South Carolina Medicaid eligibility.

  • Medicaid Office Location

  • South Carolina Department of Health and Human Services
    PO Box 8206
    Columbia, SC 29202
  • Medicaid Office Phone Number

  • The phone number to call the South Carolina Medicaid office is 888-549-0820 or in state call 803-898-2500.
  • Medicaid Online

  • To view the website for South Carolina Medicaid online, click here.